TW-37

Name: TW-37
SKU: A10955
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A10955

Bcl-2 抑制剂

TW-37，一种小分子Bcl-2抑制剂，通过涉及Notch-1和Jagged-1的失活的新途径，抑制胰腺癌细胞生长并诱导凋亡。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥385.00	现货
10mg	¥525.00	现货
25mg	¥1,015.00	现货
50mg	¥1,715.00	现货
100mg	¥2,765.00	现货
*10mM 1mL in DMSO**	¥630.00	现货
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Data Sheet

SDS

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生物活性

Discription

TW-37, a small-molecule inhibitor of Bcl-2, inhibits cell growth and induces apoptosis in pancreatic cancer mediated through a novel pathway involving inactivation of Notch-1 and Jagged-1.

Targets

Target	Value

产品信息

目录号	A10955
分子式	C33H35NO6S
分子量	573.7
CAS号	877877-35-5
SMILES	CC(C)C1=CC=CC=C1CC2=C(C(=C(C(=C2)C(=O)NC3=CC=C(C=C3)S(=O)(=O)C4=CC=CC=C4C(C)(C)C)O)O)O
其他名称	TW37
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	110 mg/mL (191.73 mM)
	Water	Insoluble
	Ethanol	4 mg/mL (6.97 mM)
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.43 mL	87.15 mL	174.31 mL
0.5 mM	3.49 mL	17.43 mL	34.86 mL
1 mM	1.74 mL	8.72 mL	17.43 mL
5 mM	0.35 mL	1.74 mL	3.49 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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