Tyk2-IN-8

Name: Tyk2-IN-8
SKU: A19052
Price: 1645 CNY
Rating: 5 (288 reviews)

目录号: A19052

TYK2 抑制剂

Tyk2-IN-8（化合物10）是一种选择性的 TYK2 抑制剂，它与 TYK2 催化活性的 JH1 域结合，具有 17 nM 的 IC50，用于治疗银屑病（牛皮癣）。

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Grouped product items
规格	价格	库存
1mg	¥1,645.00	现货
2mg	¥2,520.00	现货
5mg	¥3,570.00	现货
10mg	¥5,180.00	现货
25mg	¥8,085.00	现货
50mg	¥10,955.00	现货
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Data Sheet

SDS

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生物活性

Discription	Tyk2-IN-8 (compound 10) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain with an IC50 of 17 nM, used in the treatment of psoriasis.

产品信息

目录号	A19052
分子式	C20H17N9
分子量	383.41
CAS号	2127109-84-4
SMILES	N#CC[C@@]1(N2N=CC(C3=NC(C4=CN(C)N=C4)=CN5C3=CC=N5)=C2)C[C@H](C#N)C1
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	72 mg/mL (187.78 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.08 mL	130.41 mL	260.82 mL
0.5 mM	5.22 mL	26.08 mL	52.16 mL
1 mM	2.61 mL	13.04 mL	26.08 mL
5 mM	0.52 mL	2.61 mL	5.22 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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