U0126-EtOH

Name: U0126-EtOH
SKU: A10957
Price: 175 CNY
Rating: 5 (5 reviews)

目录号: A10957

MEK 抑制剂

5 篇发表文献

U0126-EtOH 是一种同时抑制 MEK1 和 MEK2 的抑制剂，其半抑制浓度（IC50）分别为 72 nM 和 58 nM。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥280.00	现货
25mg	¥385.00	现货
50mg	¥490.00	现货
100mg	¥630.00	现货
250mg	¥1,225.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用U0126-EtOH发表的5篇文献

Ji Wang, .et al. , Acta Pharmacol Sin, 2024, Nov 20 PMID: 39567750

Hanna Galganska, .et al. , Cell Mol Life Sci, 2021, Dec;78(24):8229-8242 PMID: 34741187

Paul Mark Medina, .et al. , Transl Oncol, 2021, Jan;14(1):100940 PMID: 33221682

Byungki Jang, .et al. , Int J Mol Sci, 2017, Nov; 18(11): 2258 PMID: 29077055

Choe YJ, .et al. , Int J Oncol., 2014, 44(3):761-8. PMID: 24366007

生物活性

Discription

U0126-EtOH is an inhibitor of both MEK1 and MEK2 with an IC50 of 72 nM and 58 nM respectively.

Targets

Target	Value

产品信息

目录号	A10957
分子式	C18H16N6S2.C2H6O
分子量	426.6
CAS号	1173097-76-1
SMILES	CCO.C1=CC=C(C(=C1)N)S/C(=C(/C(=C(/SC2=CC=CC=C2N)\N)/C#N)\C#N)/N
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 77 mg/mL (180.51 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5%DMSO+40%PEG300+5%Tween 80+50%H2O	4.03 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.44 mL	117.21 mL	234.41 mL
0.5 mM	4.69 mL	23.44 mL	46.88 mL
1 mM	2.34 mL	11.72 mL	23.44 mL
5 mM	0.47 mL	2.34 mL	4.69 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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