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UAMC 00039 dihydrochloride是二肽基肽酶II（DPP-II）的有效抑制剂（IC50 = 0.48 nM）。展示了DPP-II对DPP-9，DPP-8和DPP-IV的选择性（IC50值分别为78.6、142和165μM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.13 mL | 130.63 mL | 261.26 mL |
| 0.5 mM | 5.23 mL | 26.13 mL | 52.25 mL |
| 1 mM | 2.61 mL | 13.06 mL | 26.13 mL |
| 5 mM | 0.52 mL | 2.61 mL | 5.23 mL |
*The above data is based on the productmolecular weight 382.76. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16047 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 382.76 |
| Formula | C16H24ClN3O.2HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 697797-51-6 |
| Synonyms | Uamc00039 dihydrochloride |
| SMILES | ClC1=CC=C(C=C1)CNCC[C@@H](C(N2CCCCC2)=O)N.Cl.Cl |
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