Signaling Pathway
重要通知：仅供研究使用。我们不向患者销售。
| Discription | Ubenimex, also known as NK 421 and Bestatin, is a CD13 inhibitor. Ubenimex attenuates acquired sorafenib resistance in renal cell carcinoma by inhibiting Akt signaling in a lipophagy associated mechanism. Ubenimex synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma. Ubenimex inhibits cell proliferation, migration and invasion by inhibiting the expression of APN and inducing autophagic cell death in prostate cancer cells. | |||||
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| Cell Research |
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| 目录号 | A10958 |
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| 分子式 | C16H24N2O4 |
| 分子量 | 308.378 |
| CAS号 | 58970-76-6 |
| SMILES | CC(C)C[C@@H](C(O)=O)NC([C@@H](O)[C@H](N)CC1=CC=CC=C1)=O |
| 其他名称 | Ubenimex, NK 421, NK-421, NK421, Bestatin, NSC 265489, NSC265489, NSC-265489 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 0.35 mg/mL (1.13 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.43 mL | 162.14 mL | 324.28 mL |
| 0.5 mM | 6.49 mL | 32.43 mL | 64.86 mL |
| 1 mM | 3.24 mL | 16.21 mL | 32.43 mL |
| 5 mM | 0.65 mL | 3.24 mL | 6.49 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
