UCN-02
目录号: A19279
PKC inhibitor
UCN-02(7-epi-羟基司他斯普烷)是由链霉菌株N-12产生的一种选择性蛋白激酶C(PKC)抑制剂,其对PKC和蛋白激酶A(PKA)的IC50分别为62 nM和250 nM。
Discription | UCN-02 (7-epi-Hydroxystaurosporine) is a selective protein kinase C (PKC) inhibitor produced by Streptomyces strain N-12, with IC50s of 62 nM and 250 nM for PKC and protein kinase A (PKA), respectively. |
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目录号 | A19279 |
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分子式 | C28H26N4O4 |
分子量 | 482.53 |
CAS号 | 121569-61-7 |
SMILES | O=C1C2=C([C@H](O)N1)C3=C(N4C5=C3C=CC=C5)C6=C2C7=CC=CC=C7N6[C@]8([H])O[C@@]4(C)[C@H](OC)[C@H](NC)C8 |
其他名称 | 7-epi-Hydroxystaurosporine, UCN02, UCN 02 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2