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UK-383367是一种前胶原C蛋白酶抑制剂，IC50为44 nM，对MMP具有优异的选择性。
| In vitro (25°C) | DMSO | 56 mg/mL (172.64 mM) | |
| Water | Insoluble | ||
| Ethanol | 56 mg/mL (172.64 mM) | ||
| In vivo | 15% Captisol | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.83 mL | 154.13 mL | 308.26 mL |
| 0.5 mM | 6.17 mL | 30.83 mL | 61.65 mL |
| 1 mM | 3.08 mL | 15.41 mL | 30.83 mL |
| 5 mM | 0.62 mL | 3.08 mL | 6.17 mL |
*The above data is based on the productmolecular weight 324.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10959 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 324.4 |
| Formula | C15H24N4O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 348622-88-8 |
| Synonyms | UK383367 |
| SMILES | C1CCC(CC1)CCC[C@H](CC(=O)NO)C2=NC(=NO2)C(=O)N |
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