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UM-164

产品详情

生物活性

UM-164 (DAS-DFGO-II) is a highly potent inhibitor of c-Src with a Kd of 2.7 nM. UM-164 also potently inhibits p38α and p38β.

溶解度 *

In vitro	DMSO	85 mg/mL (132.67 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.61 mL	78.04 mL	156.08 mL
0.5 mM	3.12 mL	15.61 mL	31.22 mL
1 mM	1.56 mL	7.8 mL	15.61 mL
5 mM	0.31 mL	1.56 mL	3.12 mL

*The above data is based on the productmolecular weight 640.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A19895
作用机制	Inhibitor (抑制剂)
M. Wt	640.68
Formula	C30H31F3N8O3S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	903564-48-7
Synonyms	DAS-DFGO-II, UM164, UM 164
SMILES	O=C(C1=CN=C(NC2=NC(C)=NC(N3CCN(CCO)CC3)=C2)S1)NC4=CC(NC(C5=CC=CC(C(F)(F)F)=C5)=O)=CC=C4C