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UNC-1999

目录号: A13166
EZH2/EZH1 抑制剂
UNC1999 是首个口服生物利用度高的抑制剂,对野生型和突变型 EZH2 以及 EZH1 具有高效的体外活性。
Grouped product items
规格 价格 库存 数量
1mg
¥175.00
现货
2mg
¥245.00
现货
5mg
¥385.00
现货
10mg
¥630.00
现货
25mg
¥1,260.00
现货
50mg
¥2,065.00
现货
100mg
¥3,745.00
现货
500mg
¥8,295.00
现货
10mM * 1mL in DMSO
¥595.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用UNC-1999发表的1篇文献
  • Guang Bai, .et al. , Epigenetics of Chronic Pain, 2019, Pages 1-48
  • 生物活性
    Discription UNC1999 is the first orally bioavailable inhibitor that has high in vitro potency for wildtype and mutant EZH2 as well as EZH1.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A13166
    分子式 C33H43N7O2
    分子量 569.74
    CAS号 1431612-23-5
    SMILES CCCC1=C(C(=O)NC(=C1)C)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CN=C(C=C4)N5CCN(CC5)C(C)C)C(C)C
    其他名称 UNC 1999, UNC1999
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 17 mg/mL (29.84 mM)
    Water Insoluble
    Ethanol 43 mg/mL (75.47 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 17.55 mL 87.76 mL 175.52 mL
    0.5 mM 3.51 mL 17.55 mL 35.1 mL
    1 mM 1.76 mL 8.78 mL 17.55 mL
    5 mM 0.35 mL 1.76 mL 3.51 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
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