UPGL00004
目录号: A19047
GAC 抑制剂
UPGL00004 是一种强效的异构酶谷氨酰胺酶C(GAC)抑制剂(IC50=29 nM; Kd=27 nM)。UPGL00004 强烈抑制高侵袭性三阴性乳腺癌细胞系的增殖。
Discription | UPGL00004 is a potent allosteric glutaminase C (GAC) inhibitor (IC50=29 nM; Kd=27 nM). UPGL00004 strongly inhibits the proliferation of highly aggressive triple-negative breast cancer cell lines. | |||||
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Cell Research |
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目录号 | A19047 |
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分子式 | C25H26N8O2S2 |
分子量 | 534.66 |
CAS号 | 1890169-95-5 |
SMILES | O=C(NC1=NN=C(N2CCC(NC3=NN=C(NC(CC4=CC=CC=C4)=O)S3)CC2)S1)CC5=CC=CC=C5 |
其他名称 | UPGL 00004, UPGL-00004 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 22 mg/mL (41.14 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 18.7 mL | 93.52 mL | 187.03 mL |
0.5 mM | 3.74 mL | 18.7 mL | 37.41 mL |
1 mM | 1.87 mL | 9.35 mL | 18.7 mL |
5 mM | 0.37 mL | 1.87 mL | 3.74 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2