Valecobulin
目录号: A21242
β-tubulin polymerization 抑制剂
Valecobulin(CKD516)是(S516)的缬氨酸前药,也是一种血管破坏剂(VDA)。Valecobulin 是一种强效的 β-微管聚合抑制剂,对小鼠和人类实体瘤具有显著的抗肿瘤活性。
Discription | Valecobulin (CKD516) is a valine prodrug of (S516) and a vascular disrupting agent (VDA). Valecobulin is a potent β-tubulin polymerization inhibitor with marked antitumor activity against murine and human solid tumors. | |||||
---|---|---|---|---|---|---|
Cell Research |
|
目录号 | A21242 |
---|---|
分子式 | C26H28N6O5S |
分子量 | 536.6 |
CAS号 | 1188371-47-2 |
SMILES | CC(C)[C@H](N)C(NC1=NC(C2=CC=C(C(C3=CC(OC)=C(OC)C(OC)=C3)=O)C(N4N=CN=C4)=C2)=CS1)=O |
其他名称 | CKD-516 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2