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Vasopressin antagonist 1867,可口服和选择性V1b受体拮抗剂(hV1b抑制作用的IC50值为3 nM,相对于hV1a,hV2和hOT表现出> 1000倍的选择性)。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 20.3 mL | 101.5 mL | 203 mL |
0.5 mM | 4.06 mL | 20.3 mL | 40.6 mL |
1 mM | 2.03 mL | 10.15 mL | 20.3 mL |
5 mM | 0.41 mL | 2.03 mL | 4.06 mL |
*The above data is based on the productmolecular weight 492.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A16188 |
---|---|
作用机制 | Antagonist (拮抗剂) |
M. Wt | 492.61 |
Formula | C28H36N4O4 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 909391-88-4 |
Synonyms | Compound 12i |
SMILES | CC(C)NC(=O)CN1C(=NC2=C(C1=O)C=C(C=C2)OCCCN3CCCCC3)C4=CC(=CC=C4)OC |
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