Vatalanib (PTK787) 2HCl

Name: Vatalanib (PTK787) 2HCl
SKU: A10967
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A10967

VEGFR 抑制剂

1 篇发表文献

Vatalanib（PTK787 或 PTK/ZK）是一种小分子蛋白激酶抑制剂，能够抑制血管生成。它能抑制所有已知的VEGF受体，以及血小板源性生长因子受体-β和c-kit，但对VEGFR-2的选择性最强。CAS号为212141-51-0（盐酸盐）212141-54-3（游离碱）。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥245.00	现货
25mg	¥315.00	现货
50mg	¥385.00	现货
100mg	¥490.00	现货
200mg	¥770.00	现货
*10mM 1mL in DMSO**	¥210.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Vatalanib (PTK787) 2HCl发表的1篇文献

Ayaka Kojima, .et al. , Xenobiotica, 2022, Jul;52(7):669-675 PMID: 36251932

生物活性

Discription

Vatalanib (PTK787 or PTK/ZK) is a small molecule protein kinase inhibitor that inhibits angiogenesis that inhibits all known VEGF receptors, as well as platelet-derived growth factor receptor-beta and c-kit, but is most selective for VEGFR-2. CAS: 212141-51-0 (HCl) 212141-54-3 (Free base)

Targets

Target	Value

产品信息

目录号	A10967
分子式	C20H17Cl3N4
分子量	419.7
CAS号	212141-51-0
SMILES	C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4.Cl.Cl
其他名称	Vatalanib,PTK787,PTK/ZK
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	77 mg/mL (183.45 mM)
	Water	9 mg/mL (21.44 mM)
	Ethanol	5 mg/mL (11.91 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.83 mL	119.13 mL	238.27 mL
0.5 mM	4.77 mL	23.83 mL	47.65 mL
1 mM	2.38 mL	11.91 mL	23.83 mL
5 mM	0.48 mL	2.38 mL	4.77 mL

Useful Calculator

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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