微信关注
China
Total item
Cart Subtotal
￥ 0.00 产品详情
Vatalanib (PTK787) 2HCl是一种小分子蛋白激酶抑制剂，可抑制抑制所有已知VEGF受体以及血小板衍生的生长因子受体β和c-kit的血管生成，但对VEGFR-2的选择性最高。
Targets
| Target | Value |
|---|---|
| VEGFR2/KDR | IC50: 37nM |
| VEGFR1/FLT1 | IC50: 77nM |
| VEGFR2/Flk1 | IC50: 270nM |
| PDGFRβ | IC50: 580nM |
| VEGFR3/FLT4 | IC50: 660nM |
| c-Kit | IC50: 730nM |
| c-Fms | IC50: 1.4μM |
| In vitro | DMSO | 77 mg/mL (183.45 mM) | |
| Water | 9 mg/mL (21.44 mM) | ||
| Ethanol | 5 mg/mL (11.91 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.83 mL | 119.13 mL | 238.27 mL |
| 0.5 mM | 4.77 mL | 23.83 mL | 47.65 mL |
| 1 mM | 2.38 mL | 11.91 mL | 23.83 mL |
| 5 mM | 0.48 mL | 2.38 mL | 4.77 mL |
*The above data is based on the productmolecular weight 419.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10967 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 419.7 |
| Formula | C20H17Cl3N4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 212141-51-0 |
| Synonyms | Vatalanib,PTK787,PTK/ZK |
| SMILES | C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4.Cl.Cl |
产品资料
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
Vandetanib (ZD6474)
Vandetanib (ZD6474)是一种VEGFR和EGFR拮抗剂，是一种酪氨酸激酶抑制剂，对于HUVEC增殖，PC-9细胞和酪氨酸激酶活…
Apatinib (YN968D1)
Apatinib (YN968D1)是一种酪氨酸激酶抑制剂，可选择性抑制血管内皮生长因子受体2（VEGFR2，也称为KDR），后者…
Motesanib (AMG706)
Motesanib(AMG706)是一种多激酶抑制剂，可选择性靶向VEGF受体，血小板衍生的生长因子受体（PDGFRs）和Kit受体…
TSU-68 (Orantinib, SU6668)
TSU-68 (Orantinib,SU6668)在无细胞试验中具有8 nM的Ki对PDGFR自磷酸化的最大效力，但也强烈抑制Flk-1和FGFR1反磷酸…
BMS-690514
BMS-690514是一种有效的选择性表皮生长因子受体（EGFR），HER2和HER4抑制剂，以及VEGF受体激酶。
Regorafenib (BAY 73-4506)
Regorafenib (BAY 73-4506)是一种多激酶抑制剂，IC50为17、40和69 nM c-KIT，VEGFR2，B-Raf。Regorafenib（BAY 73-4506）是一种…
Raf265 derivative
Raf265 derivative是Raf265的衍生物，Raf265是一种口服，高度选择性的RAF和VEGFR激酶抑制剂，IC50为5至10μM。
Keywords:购买 Vatalanib (PTK787) 2HCl | Vatalanib (PTK787) 2HCl 供应商 | 订购 Vatalanib (PTK787) 2HCl | Vatalanib (PTK787) 2HCl 价格 | Vatalanib (PTK787) 2HCl 生产商 | 订单 Vatalanib (PTK787) 2HCl | Vatalanib (PTK787) 2HCl 代理商 | 购买 212141-51-0| 212141-51-0 供应商 | 订购 212141-51-0 | 212141-51-0 价格 | 212141-51-0 生产商 | 订单 212141-51-0 | 212141-51-0 代理商|buy Vatalanib (PTK787) 2HCl | Vatalanib (PTK787) 2HCl Supplier | purchase Vatalanib (PTK787) 2HCl | Vatalanib (PTK787) 2HCl cost | Vatalanib (PTK787) 2HCl manufacturer | order Vatalanib (PTK787) 2HCl | Vatalanib (PTK787) 2HCl distributor | buy 212141-51-0| 212141-51-0 Supplier | purchase 212141-51-0 | 212141-51-0 cost | 212141-51-0 manufacturer | order 212141-51-0 | 212141-51-0 distributor
联系我们
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: sales@adooq.com
Not your Region? View all Distributors
ADOOQ 产品质量保证
We promise all products to perform as described.