VcMMAE

Name: VcMMAE
SKU: A14362
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A14362

VcMMAE 是一种抗体药物偶联物（ADC），通过使用抗有丝分裂剂单甲基奥里斯他汀（MMAE），通过溶酶体可裂解的二肽缬氨酸-瓜氨酸（vc）连接，具有强大的抗肿瘤活性。

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Grouped product items
规格	价格	库存
1mg	¥140.00	现货
2mg	¥210.00	现货
5mg	¥315.00	现货
10mg	¥560.00	现货
25mg	¥1,085.00	现货
50mg	¥1,785.00	现货
100mg	¥2,730.00	现货
500mg	¥6,510.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

VcMMAE is an antibody-drug conjugate (ADC) with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the lysosomally cleavable dipeptide, valine-citrulline (vc).

Targets

Target	Value

产品信息

目录号	A14362
分子式	C68H105N11O15
分子量	1316.63
CAS号	646502-53-6
SMILES	CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)NC(=O)[C@H](CCCNC(=O)N)NC(=O)[C@H](C(C)C)NC(=O)CCCCCN4C(=O)C=CC4=O
其他名称	Vedotin
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	92 mg/mL (69.87 mM)
	Water	Insoluble
	Ethanol	92 mg/mL (69.87 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	7.6 mL	37.98 mL	75.95 mL
0.5 mM	1.52 mL	7.6 mL	15.19 mL
1 mM	0.76 mL	3.8 mL	7.6 mL
5 mM	0.15 mL	0.76 mL	1.52 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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