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Vercirnon (GSK-1605786) is an orally bioavailable, selective, and potent antagonist of CCR9, with an IC50 of 10 nM, used in the research of inflammatory bowel diseases.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.48 mL | 112.38 mL | 224.75 mL |
| 0.5 mM | 4.5 mL | 22.48 mL | 44.95 mL |
| 1 mM | 2.25 mL | 11.24 mL | 22.48 mL |
| 5 mM | 0.45 mL | 2.25 mL | 4.5 mL |
*The above data is based on the productmolecular weight 444.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21315 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 444.93 |
| Formula | C22H21ClN2O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 698394-73-9 |
| Synonyms | GSK-1605786; CCX282-B; Traficet-EN |
| SMILES | O=S(C1=CC=C(C(C)(C)C)C=C1)(NC2=CC=C(Cl)C=C2C(C3=CC=[N+]([O-])C=C3)=O)=O |
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