Verteporfin

Name: Verteporfin
SKU: A12658
Price: 175 CNY
Rating: 5 (6 reviews)

目录号: A12658

YAP 抑制剂

6 篇发表文献

Verteporfin 是一种小分子，能够抑制 TEAD、YAP 关联以及 YAP 引起的肝脏过度生长。它还是一种强效的第二代光敏剂，源自卟啉。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥490.00	现货
10mg	¥735.00	现货
25mg	¥1,505.00	现货
50mg	¥2,485.00	现货
100mg	¥3,360.00	现货
*10mM 1mL in DMSO**	¥840.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Verteporfin发表的6篇文献

Shruti Vig, .et al. , Cancer Drug Resist, 2024, Sep 21:7:35 PMID: 39403604

Yu Ren, .et al. , Eur J Med Res, 2024, May 30;29(1):303 PMID: 38812041

Po-Ju Lee, .et al. , J Exp Clin Cancer Res, 2022, Aug 20;41(1):254 PMID: 35986369

Ling-Yan Liu, .et al. , Int J Mol Med, 2020, Dec;46(6):2235-2250 PMID: 33125123

Wang Y, .et al. , Toxicol Appl Pharmacol, 2019, 2019 Dec 5;387:114852 PMID: 31812773

Abe T, .et al. , Toxicol Sci, 2018, Oct 1;165(2):408-419 PMID: 29893953

生物活性

Discription

Verteporfin is a small molecule that inhibits TEAD, YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin.

Targets

Target	Value

产品信息

目录号	A12658
分子式	C41H42N4O8
分子量	718.79
CAS号	129497-78-5
SMILES	O=C(O)CCC1=C(C)C(/C=C2C(C=C)=C(C)/C(N/2)=C/3)=N/C1=C\C(N4)=C(CCC(OC)=O)C(C)=C4/C=C5[C@]6(C)[C@H](C(OC)=O)C(C(OC)=O)=CC=C6C3=N/5
其他名称	Visudyne, DB00460, CL 318,952, Benzoporphyrin D, Bpd-MA, AIDS350621, AIDS-350621, Benzoporphyrin derivative monoacid ring A.
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	89 mg/mL (123.82 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	13.91 mL	69.56 mL	139.12 mL
0.5 mM	2.78 mL	13.91 mL	27.82 mL
1 mM	1.39 mL	6.96 mL	13.91 mL
5 mM	0.28 mL	1.39 mL	2.78 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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