产品详情
Verteporfin是抑制TEAD-YAP缔合和YAP诱导的肝过度生长的小分子。它也是一种有效的第二代光敏剂,衍生自卟啉。
靶点信息
VDA (Endothelial cells) | ||||
In vitro | DMSO | 89 mg/mL (123.82 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 13.91 mL | 69.56 mL | 139.12 mL |
0.5 mM | 2.78 mL | 13.91 mL | 27.82 mL |
1 mM | 1.39 mL | 6.96 mL | 13.91 mL |
5 mM | 0.28 mL | 1.39 mL | 2.78 mL |
*The above data is based on the productmolecular weight 718.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A12658 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 718.79 |
Formula | C41H42N4O8 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 129497-78-5 |
Synonyms | Visudyne, DB00460??CL 318,952??Benzoporphyrin D??Bpd-MA??AIDS350621??AIDS-350621??Benzoporphyrin derivative monoacid ring A. |
SMILES | O=C(O)CCC1=C(C)C(/C=C2C(C=C)=C(C)/C(N/2)=C/3)=N/C1=C\C(N4)=C(CCC(OC)=O)C(C)=C4/C=C5[C@]6(C)[C@H](C(OC)=O)C(C(OC)=O)=CC=C6C3=N/5 |
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