VGX-1027
目录号: A12548
TLR4 抑制剂
VGX-1027 通过抑制 toll-like 受体 4(TLR4)信号传导,展示出免疫调节和抗炎活性。
Discription | VGX-1027 displays immunomodulatory and anti-inflammatory activities by inhibiting toll-like receptor 4 (TLR4) signaling. | ||
---|---|---|---|
Targets |
|
目录号 | A12548 |
---|---|
分子式 | C11H11NO3 |
分子量 | 205.21 |
CAS号 | 6501-72-0 |
SMILES | C1C(ON=C1C2=CC=CC=C2)CC(=O)O |
其他名称 | GIT 27, VGX1027, GIT27 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 38 mg/mL (185.17 mM) | |
Water | Insoluble | ||
Ethanol | 38 mg/mL (185.17 mM) | ||
In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 9 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 48.73 mL | 243.65 mL | 487.31 mL |
0.5 mM | 9.75 mL | 48.73 mL | 97.46 mL |
1 mM | 4.87 mL | 24.37 mL | 48.73 mL |
5 mM | 0.97 mL | 4.87 mL | 9.75 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2