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VH-298

VH-298

Name: VH-298
SKU: A20326

目录号: A20326

VHL:HIF-α interaction inhibitor

VH-298 Chemical Structure

CAS NO. 2097381-85-4

VH-298 is a highly potent inhibitor of the VHL:HIF-α interaction with a Kd value of 80 to 90 nM, used in PROTAC technology.

库存：现货

规格	价格	数量
2 mg	￥ 441.00
5 mg	￥ 882.00
10 mg	￥ 1,715.00
50 mg	￥ 5,047.00

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生物活性

VH-298 is a highly potent inhibitor of the VHL:HIF-α interaction with a Kd value of 80 to 90 nM, used in PROTAC technology.

溶解度 *

In vitro	DMSO	88 mg/mL (168.04 mM)
	Water	Insoluble
	Ethanol	88 mg/mL (168.04 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.1 mL	95.48 mL	190.97 mL
0.5 mM	3.82 mL	19.1 mL	38.19 mL
1 mM	1.91 mL	9.55 mL	19.1 mL
5 mM	0.38 mL	1.91 mL	3.82 mL

*The above data is based on the productmolecular weight 523.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20326
M. Wt	523.65
Formula	C27H33N5O4S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2097381-85-4
Synonyms	VH 298; VH298
SMILES	O=C([C@H]1N(C([C@H](C(C)(C)C)NC(C2(CC2)C#N)=O)=O)C[C@H](O)C1)NCC3=CC=C(C4=C(C)N=CS4)C=C3