VH-298

Name: VH-298
SKU: A20326
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A20326

VHL:HIF-α interaction inhibitor

VH-298 是一种高效的抑制剂，用于抑制 VHL:HIF-α 互作，其 Kd 值为 80 至 90 nM，常用于 PROTAC 技术中。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥455.00	现货
10mg	¥805.00	现货
25mg	¥1,540.00	现货
50mg	¥2,555.00	现货
100mg	¥4,305.00	现货
*10mM 1mL in DMSO**	¥525.00	现货
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Data Sheet

SDS

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生物活性

Discription	VH-298 is a highly potent inhibitor of the VHL:HIF-α interaction with a Kd value of 80 to 90 nM, used in PROTAC technology.

产品信息

目录号	A20326
分子式	C27H33N5O4S
分子量	523.65
CAS号	2097381-85-4
SMILES	O=C([C@H]1N(C([C@H](C(C)(C)C)NC(C2(CC2)C#N)=O)=O)C[C@H](O)C1)NCC3=CC=C(C4=C(C)N=CS4)C=C3
其他名称	VH 298; VH298
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	88 mg/mL (168.04 mM)
	Water	Insoluble
	Ethanol	88 mg/mL (168.04 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.1 mL	95.48 mL	190.97 mL
0.5 mM	3.82 mL	19.1 mL	38.19 mL
1 mM	1.91 mL	9.55 mL	19.1 mL
5 mM	0.38 mL	1.91 mL	3.82 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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