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Vicriviroc Malate

目录号: A10971
CCR5 拮抗剂
Vicriviroc Malate 是一种第二代口服活性 CCR5 对抗剂,同时也是一种强效的 HIV-1 进入靶细胞的抑制剂,平均 IC50 值为 0.46 nM,对 HIV 分离株(n=52)的 IC50 值为 1~10 nM。
Grouped product items
规格 价格 库存 数量
5mg
¥805.00
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10mg
¥1,365.00
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25mg
¥2,660.00
现货
50mg
¥4,165.00
现货
100mg
¥6,825.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

Other Forms of Vicriviroc Malate

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Vicriviroc Malate发表的1篇文献
  • Tomohiro Nabekura, .et al. , Antimicrob Agents Chemother, 2015, Dec; 59(12): 7666-7670 PMID: 26416870
  • 生物活性
    Discription Vicriviroc Malate is a second generation orally active CCR5 antagonist, which is also a potent inhibitor of HIV-1 entry into target cells, with a mean IC50 =0.46 nM and IC50 =1~10 nM to HIV isolates (n=52).
    产品信息
    目录号 A10971
    分子式 C28H38F3N5O2.C4H6O5
    分子量 667.7
    CAS号 541503-81-5
    SMILES C[C@H]1CN(CCN1[C@@H](COC)C2=CC=C(C=C2)C(F)(F)F)C3(CCN(CC3)C(=O)C4=C(N=CN=C4C)C)C.C(C(C(=O)O)O)C(=O)O
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 121 mg/mL (181.21 mM)
    Water 34 mg/mL (50.92 mM)
    Ethanol 121 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 14.98 mL 74.88 mL 149.77 mL
    0.5 mM 3 mL 14.98 mL 29.95 mL
    1 mM 1.5 mL 7.49 mL 14.98 mL
    5 mM 0.3 mL 1.5 mL 3 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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