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Vilazodone充当5-羟色胺再摄取抑制剂（IC50 = 0.5 nM）和5-HT1A受体部分激动剂（IC50 = 0.2 nM； IA =?60-70％）。
| In vitro | DMSO | 79 mg/mL (178.93 mM) | |
| Water | Insoluble | ||
| Ethanol | 13 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.65 mL | 113.25 mL | 226.5 mL |
| 0.5 mM | 4.53 mL | 22.65 mL | 45.3 mL |
| 1 mM | 2.27 mL | 11.33 mL | 22.65 mL |
| 5 mM | 0.45 mL | 2.27 mL | 4.53 mL |
*The above data is based on the productmolecular weight 441.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11116 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 441.5 |
| Formula | C26H27N5O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 163521-12-8 |
| Synonyms | Viibryd |
| SMILES | C1CN(CCN1CCCCC2=CNC3=C2C=C(C=C3)C#N)C4=CC5=C(C=C4)OC(=C5)C(=O)N |
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