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Vinflunine Tartrate是长春氟宁的酒石酸盐，它使微管不稳定，IC50为18.8 nM，并在细胞分裂过程中干扰微管的动力学。
靶点信息
| Microtubules | ||||
| 1.2 μM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 10.34 mL | 51.71 mL | 103.41 mL |
| 0.5 mM | 2.07 mL | 10.34 mL | 20.68 mL |
| 1 mM | 1.03 mL | 5.17 mL | 10.34 mL |
| 5 mM | 0.21 mL | 1.03 mL | 2.07 mL |
*The above data is based on the productmolecular weight 967.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10975 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 967.0 |
| Formula | C45H54F2N4O8.xC4H6O6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1201898-17-0 |
| SMILES | CC[C@@]12C=CCN3[C@@H]1[C@]4(CC3)[C@H]([C@]([C@@H]2OC(=O)C)(C(=O)OC)O)N(C5=CC(=C(C=C45)[C@]6(C[C@H]7C[C@H](CN(C7)CC8=C6NC9=CC=CC=C89)C(C)(F)F)C(=O)OC)OC)C.[C@@H]([C@H](C(=O)O)O)(C(=O)O)O |
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