Volitinib (Savolitinib, AZD-6094)
目录号: A14419
c-Met 抑制剂
Volitinib 是一种口服生物利用度的 c-Met 受体酪氨酸激酶抑制剂,具有潜在的抗肿瘤活性。
Discription | Volitinib is an orally bioavailable inhibitor of the c-Met receptor tyrosine kinase with potential antineoplastic activity. | |||||
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Cell Research |
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目录号 | A14419 |
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分子式 | C17H15N9 |
分子量 | 345.36 |
CAS号 | 1313725-88-0 |
SMILES | C[C@@H](C1=CN2C=CN=C2C=C1)N3C4=NC(=CN=C4N=N3)C5=CN(N=C5)C |
其他名称 | HMPL-504, HMPL504, HMPL504, AZD-6094, AZD 6094, AZD6094 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 14 mg/mL (40.53 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 28.96 mL | 144.78 mL | 289.55 mL |
0.5 mM | 5.79 mL | 28.96 mL | 57.91 mL |
1 mM | 2.9 mL | 14.48 mL | 28.96 mL |
5 mM | 0.58 mL | 2.9 mL | 5.79 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2