Vorasidenib

Name: Vorasidenib
SKU: A16908
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A16908

IDH1 抑制剂

Vorasidenib，也被称为 AG-881，是一种强效且选择性的口服可用抑制剂，针对细胞质中的异柠檬酸脱氢酶类型1（IDH1，IDH1 [NADP+] 可溶）和线粒体中的类型2（IDH2，异柠檬酸脱氢酶 [NADP+]，线粒体）的突变形式，具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
2mg	¥455.00	现货
5mg	¥805.00	现货
10mg	¥1,330.00	现货
25mg	¥2,590.00	现货
50mg	¥3,920.00	现货
100mg	¥5,670.00	现货
*10mM 1mL in DMSO**	¥700.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

Vorasidenib, also known as AG-881, is a potent and selective orally available inhibitor of mutated forms of both isocitrate dehydrogenase type 1 (IDH1, IDH1 [NADP+] soluble) in the cytoplasm and type 2 (IDH2, isocitrate dehydrogenase [NADP+], mitochondrial) in the mitochondria, with potential antineoplastic activity.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A16908
分子式	C14H13ClF6N6
分子量	414.74
CAS号	1644545-52-7
SMILES	C[C@@H](NC1=NC(C2=NC(Cl)=CC=C2)=NC(N[C@H](C)C(F)(F)F)=N1)C(F)(F)F
其他名称	AG-881, AG 881, AG881
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	75 mg/mL (180.83 mM)
	Water	Insoluble
	Ethanol	75 mg/mL (180.83 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.11 mL	120.56 mL	241.11 mL
0.5 mM	4.82 mL	24.11 mL	48.22 mL
1 mM	2.41 mL	12.06 mL	24.11 mL
5 mM	0.48 mL	2.41 mL	4.82 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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