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Vortioxetine (Lu AA21004) hydrobromide

Vortioxetine (Lu AA21004) hydrobromide

Name: Vortioxetine (Lu AA21004) hydrobromide
SKU: A12602

目录号: A12602

5-HT Receptor modulator

Vortioxetine (Lu AA21004) hydrobromide Chemical Structure

CAS NO. 960203-27-4

Vortioxetine (Lu AA21004) hydrobromide是一种口服多峰血清素能药物，可抑制5-HT（1A），5-HT（1B），5-HT（3A），5-HT（7）和SERT，IC50为15 nM，33 nM，3.7 nM，19 nM和1.6 nM。

库存：现货

规格	价格	数量
5 mg	￥ 490.00
10 mg	￥ 770.00
25 mg	￥ 1,960.00
50 mg	￥ 1,050.00
10mM * 1mL in DMSO	￥ 539.00

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产品详情

生物活性

靶点信息

SERT	5-HT3A	5-HT1A	5-HT7	5-HT1B
1.6 nM(Ki)	3.7 nM(Ki)	15 nM(Ki)	19 nM(Ki)	33 nM(Ki)

溶解度 *

In vitro (25°C)	DMSO	68 mg/mL (179.24 mM)
	Water	Insoluble
	Ethanol	15 mg/mL (39.54 mM)
In vivo	2% DMSO+40% PEG 300+2% Tween 80+ddH2O	6 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.36 mL	131.8 mL	263.6 mL
0.5 mM	5.27 mL	26.36 mL	52.72 mL
1 mM	2.64 mL	13.18 mL	26.36 mL
5 mM	0.53 mL	2.64 mL	5.27 mL

*The above data is based on the productmolecular weight 379.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12602
作用机制	Modulator (调节剂)
M. Wt	379.36
Formula	C18H22N2S.HBr
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	960203-27-4
Synonyms	Lu AA21004, LuAA21004, Lu-AA21004
SMILES	CC1=CC(=C(C=C1)SC2=CC=CC=C2N3CCNCC3)C.Br