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VP3.15

目录号: A18538
dual PDE7/GSK-3 抑制剂
VP3.15 是一种有效的、可口服吸收且能穿透中枢神经系统(CNS)的双重磷酸二酯酶(PDE)7- 糖原合成激酶(GSK)3 抑制剂,其 IC50 分别为 PDE7 的 1.59 微米和 GSK-3 的 0.88 微米。VP3.15 具有神经保护和神经修复活性,因此具有潜在的联合抗炎和促髓鞘再生疗法,用于治疗多发性硬化症(MS)。
Grouped product items
规格 价格 库存 数量
5mg
¥2,415.00
现货
10mg
¥4,515.00
现货
25mg
¥10,605.00
现货
50mg
¥13,825.00
现货
100mg
¥17,465.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription VP3.15 is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS).
产品信息
目录号 A18538
分子式 C20H22N4OS
分子量 366.48
CAS号 1281681-54-6
SMILES N1(CC/N=C2N=C(C3=CC=CC=C3)N(C4=CC=CC=C4)S/2)CCOCC1
其他名称 VP315, VP-3.15
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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