VP3.15

Name: VP3.15
SKU: A18538

目录号: A18538

dual PDE7/GSK-3 inhibitor

VP3.15 Chemical Structure

CAS NO. 1281681-54-6

VP3.15 is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS).

库存：现货

规格	价格	数量
5 mg	￥ 2,450.00
10 mg	￥ 4,550.00
50 mg	￥ 14,000.00

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制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.29 mL	136.43 mL	272.87 mL
0.5 mM	5.46 mL	27.29 mL	54.57 mL
1 mM	2.73 mL	13.64 mL	27.29 mL
5 mM	0.55 mL	2.73 mL	5.46 mL

*The above data is based on the productmolecular weight 366.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18538
作用机制	Inhibitor (抑制剂)
M. Wt	366.48
Formula	C20H22N4OS
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1281681-54-6
Synonyms	VP315, VP-3.15
SMILES	N1(CC/N=C2N=C(C3=CC=CC=C3)N(C4=CC=CC=C4)S/2)CCOCC1