VR23

Name: VR23
SKU: A13650
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A13650

Proteasome 抑制剂?€?

VR23 是一种小分子化合物，能强效抑制 胰蛋白酶样蛋白酶体（IC50 = 1 nM）、胰凝乳蛋白酶样蛋白酶体（IC50 = 50-100 nM）和 半胱氨酸蛋白酶样蛋白酶体（IC50 = 3μM）的活性。

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Grouped product items
规格	价格	库存
5mg	¥210.00	现货
10mg	¥280.00	现货
25mg	¥560.00	现货
50mg	¥1,050.00	现货
100mg	¥1,820.00	现货
200mg	¥2,695.00	现货
*10mM 1mL in DMSO**	¥175.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

VR23 is a small molecule that potently inhibited the activities of trypsin-like proteasomes (IC50 = 1 nM), chymotrypsin-like proteasomes (IC50 = 50-100 nM), and caspase-like proteasomes (IC50 = 3uM).

Targets

Target	Value

产品信息

目录号	A13650
分子式	C19H16ClN5O6S
分子量	477.88
CAS号	1624602-30-7
SMILES	ClC1=CC2=C(C(N3CCN(S(C4=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C4)(=O)=O)CC3)=CC=N2)C=C1
其他名称	VR-23, VR 23
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 29 mg/mL (60.68 mM)
	Water	Warmed: 5 mg/mL (10.46 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.93 mL	104.63 mL	209.26 mL
0.5 mM	4.19 mL	20.93 mL	41.85 mL
1 mM	2.09 mL	10.46 mL	20.93 mL
5 mM	0.42 mL	2.09 mL	4.19 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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