VU 0364439
目录号: A12664
GluR modulator
VU 0364439 是 mGlu4 受体的正向异构调节剂（PAM）（对人类 mGlu4 的体外 EC50 = 19.8 nM）。
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生物活性
| Discription | VU 0364439 is a positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4). | ||
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产品信息
| 目录号 | A12664 |
|---|---|
| 分子式 | C18H13Cl2N3O3S |
| 分子量 | 422.29 |
| CAS号 | 1246086-78-1 |
| SMILES | C1=CC=C(C(=C1)NS(=O)(=O)C2=C(C=C(C=C2)NC(=O)C3=CC=CC=N3)Cl)Cl |
| 其他名称 | VU0364439,VU-0364439 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 77 mg/mL (182.34 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.68 mL | 118.4 mL | 236.8 mL |
| 0.5 mM | 4.74 mL | 23.68 mL | 47.36 mL |
| 1 mM | 2.37 mL | 11.84 mL | 23.68 mL |
| 5 mM | 0.47 mL | 2.37 mL | 4.74 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1246086-78-1 | 1246086-78-1 供应商 | 1246086-78-1 花费 | 1246086-78-1 生产商 | 订购 1246086-78-1 | 1246086-78-1 代理商