VU0467154

目录号: A19842
mAChR modulator
VU0467154 是 M4 乙酰胆碱能受体(mAChR)的正向异构调节剂,能增强对 ACh 的反应,其 pEC50 分别为 7.75、6.2 和 6,针对大鼠、人类和猕猴的 M4 受体。
Grouped product items
规格 价格 库存 数量
2mg
¥525.00
现货
5mg
¥630.00
现货
10mg
¥1,050.00
现货
25mg
¥2,030.00
现货
50mg
¥3,500.00
现货
100mg
¥6,160.00
现货
10mM * 1mL in DMSO
¥840.00
现货
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生物活性
Discription VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor (mAChR), potentiating the response to ACh with pEC50s of 7.75, 6.2 and 6 for rat, human and cynomolgus monkey M4 receptor, respectively.
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A19842
分子式 C17H15F3N4O3S2
分子量 444.45
CAS号 1451993-15-9
SMILES O=C(C1=C(N)C2=C(C)C(C)=NN=C2S1)NCC3=CC=C(S(=O)(C(F)(F)F)=O)C=C3
其他名称 VU 0467154, VU-0467154
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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