VU0467154
目录号: A19842
mAChR modulator
VU0467154 是 M4 乙酰胆碱能受体(mAChR)的正向异构调节剂,能增强对 ACh 的反应,其 pEC50 分别为 7.75、6.2 和 6,针对大鼠、人类和猕猴的 M4 受体。
Discription | VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor (mAChR), potentiating the response to ACh with pEC50s of 7.75, 6.2 and 6 for rat, human and cynomolgus monkey M4 receptor, respectively. | |||||
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Cell Research |
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目录号 | A19842 |
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分子式 | C17H15F3N4O3S2 |
分子量 | 444.45 |
CAS号 | 1451993-15-9 |
SMILES | O=C(C1=C(N)C2=C(C)C(C)=NN=C2S1)NCC3=CC=C(S(=O)(C(F)(F)F)=O)C=C3 |
其他名称 | VU 0467154, VU-0467154 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2