VU0650786

Name: VU0650786
SKU: A19689
Price: 630 CNY
Rating: 5 (288 reviews)

目录号: A19689

CNS penetrant modulator

VU0650786 是一种强效且选择性的中枢神经系统渗透性 负向异构调节剂，针对 代谢型谷氨酸受体亚型3（mGlu3 NAM），具有 392 nM 的 IC50 值。VU0650786 在啮齿动物中显示出抗抑郁和抗焦虑活性。

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Grouped product items
规格	价格	库存
1mg	¥630.00	现货
5mg	¥1,680.00	现货
10mg	¥2,380.00	现货
25mg	¥4,060.00	现货
50mg	¥5,845.00	现货
100mg	¥8,085.00	现货
*10mM 1mL in DMSO**	¥1,855.00	现货
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Data Sheet

SDS

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生物活性

Discription

VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents.

Targets

Target	Value

产品信息

目录号	A19689
分子式	C18H15ClFN5O2
分子量	387.8
CAS号	1809085-30-0
SMILES	ClC1=CN=C(OCC2=NN([C@H](C)CN(C3=C(F)N=CC=C3)C4=O)C4=C2)C=C1
其他名称	VU 0650786, VU-0650786
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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