VU590
目录号: A22612
ROMK 抑制剂
VU590 是一种效力强大且选择性适中的 ROMK (Kir1.1) 抑制剂,其 IC50 为 290 nM。VU590 同时也能抑制 Kir7.1,其 IC50 为 8 μM。VU590 并不是评估肾脏中 ROMK 功能的好工具。
ROMK 抑制剂
Discription | VU590 is a potent and moderately selective ROMK (Kir1.1) inhibitor, with an IC50 of 290 nM. VU590 also inhibits Kir7.1, with an IC50 of 8 μM. VU590 is not a good probe of ROMK function in the kidney. |
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目录号 | A22612 |
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分子式 | C24H32N4O7 |
分子量 | 489 |
CAS号 | 313505-85-0 |
SMILES | [O-][N+](C1=CC=C(C=C1)CN(CCOCCOCC2)CCOCCN2CC(C=C3)=CC=C3[N+]([O-])=O)=O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2