VU6005806
目录号: A18488
M4 modulator
VU6005806 (AZN-00016130) 是一种强效的毒蕈碱乙酰胆碱受体4型(M4)正向异构调节剂(PAM),其对人类、大鼠、狗和猕猴的M4的EC50分别为94 nM、28 nM、87 nM和68 nM。用于神经精神疾病研究。
Discription | VU6005806 (AZN-00016130) is a potent muscarnic acethylcholine receptor subtype 4 (M4) positive allosteric modulator (PAM), with EC50s of 94 nM, 28 nM, 87 nM and 68 nM for human, rat, dog and cyno M4, respectively. Used in the research of neuropsychiatric disorders. |
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目录号 | A18488 |
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分子式 | C17H16F3N7O2S |
分子量 | 439.41 |
CAS号 | 2180914-37-6 |
SMILES | NC1=C(C(NC2CN(C3=NC=C(C(F)(F)F)C=N3)C2)=O)SC4=NN=C(OC)C(C)=C41 |
其他名称 | VU 6005806, VU-6005806, AZN00016130, AZN 00016130 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2