VU661013
目录号: A18363
MCL-1 Inhibitor
VU661013 是一种 MCL-1 抑制剂，与 Venetoclax 结合使用，可以挽救对 Venetoclax 产生抗药性的急性髓系白血病。
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生物活性
| Discription | VU661013 is a MCL-1 Inhibitor Combined with Venetoclax Rescues Venetoclax Resistant Acute Myelogenous Leukemia. | |||||
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| Targets |
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| Cell Research |
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产品信息
| 目录号 | A18363 |
|---|---|
| 分子式 | C39H39Cl2N5O4 |
| 分子量 | 712.672 |
| CAS号 | 2131184-57-9 |
| SMILES | C[C@@H]1CN(C(=O)C2=C(C3=C(N12)C(=C(C=C3)Cl)C4=C(N(N=C4C)C)C)CCCOC5=CC(=C(C(=C5)C)Cl)C)C6=CN(C7=C6C=C(C=C7)C(=O)O)C |
| 其他名称 | VU661013; VU-661013; VU 661013; |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 93 mg/mL (130.49 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.03 mL | 70.16 mL | 140.32 mL |
| 0.5 mM | 2.81 mL | 14.03 mL | 28.06 mL |
| 1 mM | 1.4 mL | 7.02 mL | 14.03 mL |
| 5 mM | 0.28 mL | 1.4 mL | 2.81 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 2131184-57-9 | 2131184-57-9 供应商 | 2131184-57-9 花费 | 2131184-57-9 生产商 | 订购 2131184-57-9 | 2131184-57-9 代理商