VX-702

Name: VX-702
SKU: A10982
Price: 245 CNY
Rating: 5 (1 reviews)

目录号: A10982

p38 MAPK 抑制剂

1 篇发表文献

VX-702 是一种口服生物可利用的 p38 MAP激酶 抑制剂，能够抑制血小板激动剂诱导的 p38 激活（IC50= 4 至 20 nM）。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥245.00	现货
25mg	¥490.00	现货
50mg	¥665.00	现货
100mg	¥1,295.00	现货
200mg	¥2,170.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用VX-702发表的1篇文献

Wei-Chun HuangFu, etc. Inflammatory signaling compromises cell responses to interferon alpha. Oncogene. 2012 Jan 12; 31(2): 161?€?172.

生物活性

Discription	VX-702 is an orally bioavailable inhibitor of p38 MAP kinase that inhibits platelet agonist induced p38 activation (IC50= 4 to 20 nM).

产品信息

目录号	A10982
分子式	C19H12F4N4O2
分子量	404.3
CAS号	479543-46-9, 745833-23-2
SMILES	C1=CC(=C(C(=C1)F)N(C2=NC(=C(C=C2)C(=O)N)C3=C(C=C(C=C3)F)F)C(=O)N)F
其他名称	VX702, VX 702
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	77 mg/mL (190.45 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.73 mL	123.67 mL	247.34 mL
0.5 mM	4.95 mL	24.73 mL	49.47 mL
1 mM	2.47 mL	12.37 mL	24.73 mL
5 mM	0.49 mL	2.47 mL	4.95 mL

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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