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Neflamapimod (VX-745)

目录号: A10983
p38 MAPK 抑制剂
VX-745 是一种小分子抑制剂,针对 MAPK(丝裂原活化蛋白激酶)具有活性,据报道它能够抑制多种 p38 MAPK 异构体,包括 p38αp38βp38γ
Grouped product items
规格 价格 库存 数量
5mg
¥245.00
现货
10mg
¥455.00
现货
25mg
¥840.00
现货
50mg
¥1,470.00
现货
100mg
¥2,205.00
现货
200mg
¥3,325.00
现货
10mM * 1mL in DMSO
¥280.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
生物活性
Discription VX-745 is a small-molecule inhibitor of MAPK that is reported to be active against several isotypes of p38 MAPK, including p38α, p38βand p38γ .
Targets
Target Value
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A10983
分子式 C19H9Cl2F2N3OS
分子量 436.3
CAS号 209410-46-8
SMILES C1=CC(=C(C(=C1)Cl)C2=C3C=CC(=NN3C=NC2=O)SC4=C(C=C(C=C4)F)F)Cl
其他名称 VX745
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro (25°C) DMSO 15 mg/mL (34.38 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.92 mL 114.6 mL 229.2 mL
0.5 mM 4.58 mL 22.92 mL 45.84 mL
1 mM 2.29 mL 11.46 mL 22.92 mL
5 mM 0.46 mL 2.29 mL 4.58 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

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    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

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    C2

    V2

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