Turofexorate isopropyl (WAY-362450)

Name: Turofexorate isopropyl (WAY-362450)
SKU: A11186
Price: 210 CNY
Rating: 5 (2 reviews)

目录号: A11186

FXR 激动剂

2 篇发表文献

WAY-362450 是一种高效、选择性强且口服生物利用度高的法尼酮X受体（FXR）激动剂（EC50：4 nM，效率=149%）。

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Grouped product items
规格	价格	库存
5mg	¥210.00	现货
10mg	¥315.00	现货
25mg	¥700.00	现货
50mg	¥1,085.00	现货
100mg	¥1,785.00	现货
200mg	¥2,695.00	现货
*10mM 1mL in DMSO**	¥245.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Turofexorate isopropyl (WAY-362450)发表的2篇文献

Dong-Hyun Kim, .et al. , Cell Death Dis, 2021, Apr; 12(4): 320 PMID: 33767132

Dong-Hyun Kim, .et al. , FASEB J, 2019, Jul 12:fj201900325R PMID: 31298930

生物活性

Discription

WAY-362450 is a highly potent, selective, and orally bioavailable farnesoid X receptor (FXR) agonist (EC50: 4 nM, eff=149%).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11186
分子式	C25H24F2N2O3
分子量	438.47
CAS号	629664-81-9
SMILES	CC(C)OC(=O)C1=CN(CC(C2=C1NC3=CC=CC=C32)(C)C)C(=O)C4=CC(=C(C=C4)F)F
其他名称	WAY362450, XL335
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 31 mg/mL (70.7 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (4.56 mM)
In vivo	NMP+PEG300 (10+90, v+v)	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.81 mL	114.03 mL	228.07 mL
0.5 mM	4.56 mL	22.81 mL	45.61 mL
1 mM	2.28 mL	11.4 mL	22.81 mL
5 mM	0.46 mL	2.28 mL	4.56 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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