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Wedelolactone是最初从白花苜蓿中提取的化合物，已显示出抑制caspase-11的作用，而caspase-11是促炎性细胞因子IL-1β成熟和病理性细胞凋亡的关键调节剂。
| In vitro | DMSO | 60 mg/mL (190.92 mM) | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.82 mL | 159.08 mL | 318.17 mL |
| 0.5 mM | 6.36 mL | 31.82 mL | 63.63 mL |
| 1 mM | 3.18 mL | 15.91 mL | 31.82 mL |
| 5 mM | 0.64 mL | 3.18 mL | 6.36 mL |
*The above data is based on the productmolecular weight 314.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14804 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 314.3 |
| Formula | C16H10O7 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 524-12-9 |
| Synonyms | IKK Inhibitor II, Eclipta alba |
| SMILES | COC1=CC(=C2C(=C1)OC(=O)C3=C2OC4=CC(=C(C=C43)O)O)O |
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