Wedelolactone

Name: Wedelolactone
SKU: A14804
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A14804

IKK 抑制剂 II

1 篇发表文献

Wedelolactone（威德罗内酮），最初从印度旱莲草（Eclipta alba）中提取的化合物，已被证实能够抑制 caspase-11，这是调控促炎症细胞因子 IL-1β 成熟和病理性凋亡的关键调节因子。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
5mg	¥420.00	现货
10mg	¥770.00	现货
25mg	¥1,330.00	现货
50mg	¥2,380.00	现货
100mg	¥3,150.00	现货
500mg	¥7,385.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Wedelolactone发表的1篇文献

Shigetoshi Yokoyama, .et al. , eLife, 2018, 7: e37854 PMID: 30526845

生物活性

Discription

Wedelolactone, a compound originally extracted from Eclipta alba, has been shown to inhibit caspase-11, which is a key regulator of proinflammatory cytokine IL-1β maturation and pathological apoptosis.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A14804
分子式	C16H10O7
分子量	314.3
CAS号	524-12-9
SMILES	COC1=CC(=C2C(=C1)OC(=O)C3=C2OC4=CC(=C(C=C43)O)O)O
其他名称	IKK Inhibitor II, Eclipta alba
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	60 mg/mL (190.92 mM)
	* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.82 mL	159.08 mL	318.17 mL
0.5 mM	6.36 mL	31.82 mL	63.63 mL
1 mM	3.18 mL	15.91 mL	31.82 mL
5 mM	0.64 mL	3.18 mL	6.36 mL

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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