WM-1119
目录号: A16828
lysine acetyltransferase KAT6A 抑制剂
WM-1119 是一种高效、选择性的赖氨酸乙酰转移酶 KAT6A 抑制剂,其 IC50 为 0.25 μM。与 KAT5 或 KAT7 相比,其活性分别高出 1,100 倍和 250 倍。
Discription | WM-1119 is a highly potent, selective inhibitor of lysine acetyltransferase KAT6A with IC50 of 0.25 μM. It is 1,100-fold and 250-fold more active against KAT6A than against KAT5 or KAT7, respectively. |
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目录号 | A16828 |
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分子式 | C18H13F2N3O3S |
分子量 | 389.38 |
CAS号 | 2055397-28-7 |
SMILES | O=C(NNS(=O)(C1=CC=CC=C1F)=O)C2=CC(C3=NC=CC=C3)=CC(F)=C2 |
其他名称 | WM 1119, WM1119 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 69 mg/mL (177.2 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 25.68 mL | 128.41 mL | 256.82 mL |
0.5 mM | 5.14 mL | 25.68 mL | 51.36 mL |
1 mM | 2.57 mL | 12.84 mL | 25.68 mL |
5 mM | 0.51 mL | 2.57 mL | 5.14 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2