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BML-284 (Wnt agonist 1)是细胞可渗透的Wnt信号传导活化剂。它诱导β-catenin和TCF依赖性转录活性，EC50值为0.7 uM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.54 mL | 142.71 mL | 285.41 mL |
| 0.5 mM | 5.71 mL | 28.54 mL | 57.08 mL |
| 1 mM | 2.85 mL | 14.27 mL | 28.54 mL |
| 5 mM | 0.57 mL | 2.85 mL | 5.71 mL |
*The above data is based on the productmolecular weight 350.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15851 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 350.37 |
| Formula | C19H18N4O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 853220-52-7 |
| Synonyms | BML-284, BML284, BML 284 |
| SMILES | COC1=CC=CC(C2=CC(NCC3=CC=C(OCO4)C4=C3)=NC(N)=N2)=C1 |
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