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WP1066

目录号: A11795

JAK2 抑制剂

WP1066 是一种新型的 JAK2 抑制剂,它能抑制携带 JAK2 V617F 突变的红细胞人类细胞的增殖,并诱导凋亡。
Grouped product items
规格 价格 库存 数量
5mg
¥245.00
现货
10mg
¥385.00
现货
25mg
¥875.00
现货
50mg
¥1,435.00
现货
100mg
¥2,170.00
现货
500mg
¥5,320.00
现货
10mM * 1mL in DMSO
¥280.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用WP1066发表的1篇文献
  • Simona Moravcova, .et al. , Life (Basel), 2021, Oct 18;11(10):1105 PMID: 34685476
  • 生物活性
    Discription WP1066 is a novel JAK2 inhibitor and it suppresses proliferation and induces apoptosis in eythroid human cells carrying the JAK2 V617F mutation.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A11795
    分子式 C17H14BrN3O
    分子量 356.2
    CAS号 857064-38-1
    SMILES C[C@@H](C1=CC=CC=C1)NC(=O)/C(=C/C2=NC(=CC=C2)Br)/C#N
    其他名称 WP 1066, WP-1066
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro DMSO 64 mg/mL (179.66 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 28.07 mL 140.37 mL 280.74 mL
    0.5 mM 5.61 mL 28.07 mL 56.15 mL
    1 mM 2.81 mL 14.04 mL 28.07 mL
    5 mM 0.56 mL 2.81 mL 5.61 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
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