WS-383
目录号: A21483
DCN1-UBC12 interaction inhibitor
WS-383 是一种强效、选择性且可逆的 DCN1-UBC12 互作抑制剂,其 IC50 为 11 nM。WS-383 抑制 Cul3/1 neddylation,诱导 p21、p27 和 NRF2 的积累。
Discription | WS-383 is a potent, selective and reversible inhibitor of DCN1-UBC12 interaction, with an IC50 of 11 nM. WS-383 inhibits Cul3/1 neddylation, induces accumulation of p21, p27 and NRF2. |
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目录号 | A21483 |
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分子式 | C18H21Cl2N9S2 |
分子量 | 498.46 |
CAS号 | 2247544-02-9 |
SMILES | CN(C)CCN1N=NN=C1SC2=CC(C)=NC3=NC(SCC4=CC=C(Cl)C=C4)=NN23.Cl |
其他名称 | WS383, WS 383 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2