WZ811
目录号: A12588
CXCR4 拮抗剂
WZ811 是一种 C-X-C 趋化因子受体 4 (CXCR4) 拮抗剂(EC50 = 0.3 nM)。它能够抑制 CXCR4/基质细胞源性因子-1(SDF-1)介导的 cAMP 调节作用(EC50 = 1.2 nM)。
Discription | WZ811 is a C-X-C chemokine receptor type 4 (CXCR4) antagonist (EC50 = 0.3 nM). Inhibits CXCR4/stromal cell-derived factor-1 (SDF-1)-mediated modulation of cAMP in vitro (EC50 = 1.2 nM). | |||||
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Cell Research |
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目录号 | A12588 |
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分子式 | C18H18N4 |
分子量 | 290.36 |
CAS号 | 55778-02-4 |
SMILES | C1=CC=NC(=C1)NCC2=CC=C(C=C2)CNC3=CC=CC=N3 |
其他名称 | WZ811; WZ-811; WZ 811. |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 29 mg/mL (99.88 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 34.44 mL | 172.2 mL | 344.4 mL |
0.5 mM | 6.89 mL | 34.44 mL | 68.88 mL |
1 mM | 3.44 mL | 17.22 mL | 34.44 mL |
5 mM | 0.69 mL | 3.44 mL | 6.89 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2