产品详情
Xanthohumol是一种来自啤酒花的烯丙基查尔酮,可抑制COX-1和COX-2活性并显示化学预防作用。
靶点信息
COX-1 | COX-2 | |||
In vitro (25°C) | DMSO | 67 mg/mL (189.05 mM) | |
Water | Insoluble | ||
Ethanol | 67 mg/mL (189.05 mM) | ||
In vivo | 0.05% (w+w) xanthohumol powder in diet, or suspended in ethanol (2.5 mg+mL) | 12 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 28.22 mL | 141.08 mL | 282.17 mL |
0.5 mM | 5.64 mL | 28.22 mL | 56.43 mL |
1 mM | 2.82 mL | 14.11 mL | 28.22 mL |
5 mM | 0.56 mL | 2.82 mL | 5.64 mL |
*The above data is based on the productmolecular weight 354.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A15919 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 354.4 |
Formula | C21H22O5 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 6754-58-1 |
SMILES | CC(=CCC1=C(C=C(C(=C1O)C(=O)C=CC2=CC=C(C=C2)O)OC)O)C |
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