XAV 939
XAV 939 是一种 TNKS 抑制剂（对于 TNKS1 和 TNKS2 的 IC50 值分别为 0.011 和 0.004 微米）。
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生物活性
| Discription | XAV 939 is a TNKS inhibitor (IC50 values are 0.011 and 0.004 μM for TNKS1 and TNKS2 respectively). | |||||
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| Cell Research |
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产品信息
| 目录号 | A10994 |
|---|---|
| 分子式 | C14H11F3N2OS |
| 分子量 | 312.3 |
| CAS号 | 284028-89-3 |
| SMILES | C1CSCC2=C1NC(=NC2=O)C3=CC=C(C=C3)C(F)(F)F |
| 其他名称 | XAV939, XAV-939 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 12 mg/mL (38.42 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 4% DMSO+corn oil | 1 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.02 mL | 160.1 mL | 320.2 mL |
| 0.5 mM | 6.4 mL | 32.02 mL | 64.04 mL |
| 1 mM | 3.2 mL | 16.01 mL | 32.02 mL |
| 5 mM | 0.64 mL | 3.2 mL | 6.4 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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