XL-888

Name: XL-888
SKU: A11251
Price: 245 CNY
Rating: 5 (2 reviews)

目录号: A11251

HSP90 抑制剂

2 篇发表文献

XL888 是一种口服生物利用度高的、ATP竞争性的、小分子抑制剂，针对热休克蛋白90（Hsp90）具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
5mg	¥735.00	现货
10mg	¥1,365.00	现货
25mg	¥2,730.00	现货
50mg	¥4,130.00	现货
100mg	¥6,020.00	现货
*10mM 1mL in DMSO**	¥980.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用XL-888发表的2篇文献

?zlem Kaplan, .et al. , Med Oncol, 2024, Jul 3;41(8):194 PMID: 38958814

Ozlem Kaplan, .et al. , Med Oncol, 2023, Oct 4;40(11):318 PMID: 37794195

生物活性

Discription

XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11251
分子式	C29H37N5O3
分子量	503.63
CAS号	1149705-71-4
SMILES	CCC(C)NC1=CC(=C(C=C1C(=O)N)C)C(=O)NC2C[C@H]3CC[C@@H](C2)N3C4=NC=C(C=C4)C(=O)C5CC5
其他名称	XL888; XL-888; XL 888
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	99 mg/mL (196.56 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.86 mL	99.28 mL	198.56 mL
0.5 mM	3.97 mL	19.86 mL	39.71 mL
1 mM	1.99 mL	9.93 mL	19.86 mL
5 mM	0.4 mL	1.99 mL	3.97 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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