XL147 analogue

Name: XL147 analogue
SKU: A10995
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A10995

PI3K 抑制剂

1 篇发表文献

XL147 是一种强效、选择性且可口服生物利用的小分子抑制剂，针对 I类磷脂酰肌醇3激酶（PI3K），具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥315.00	现货
10mg	¥525.00	现货
25mg	¥945.00	现货
50mg	¥1,540.00	现货
100mg	¥2,695.00	现货
200mg	¥3,535.00	现货
*10mM 1mL in DMSO**	¥560.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用XL147 analogue发表的1篇文献

Yushi Hayashida, .et al. , Int J Cancer, 2016, Aug 1;139(3):700-11 PMID: 26989815

生物活性

Discription

XL147 is a potent, selective and orally bioavailable small molecule inhibitor of class I phosphatidylinositol 3 kinase (PI3K) with potential antineoplastic activity.

Targets

Target	Value

产品信息

目录号	A10995
分子式	C21H16N6O2S2
分子量	448.5
CAS号	956958-53-5
SMILES	CC1=CC=C(C=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=CC5=NSN=C5C=C4
其他名称	XL-147, SAR245408
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	3 mg/mL (6.68 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	14 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.3 mL	111.48 mL	222.97 mL
0.5 mM	4.46 mL	22.3 mL	44.59 mL
1 mM	2.23 mL	11.15 mL	22.3 mL
5 mM	0.45 mL	2.23 mL	4.46 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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