XL388
目录号: A12395
mTOR 抑制剂
XL388 是一种新型的、高效的、选择性的、ATP竞争性的、可口服的哺乳动物雷帕霉素靶蛋白(mTOR)抑制剂。
Discription | XL388 is a Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR). | |||||
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Targets |
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Cell Research |
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目录号 | A12395 |
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分子式 | C23H22FN3O4S |
分子量 | 455.5 |
CAS号 | 1251156-08-7 |
SMILES | CC1=C(C=CC(=C1F)S(=O)(=O)C)C(=O)N2CCOC3=C(C2)C=C(C=C3)C4=CN=C(C=C4)N |
其他名称 | XL 388, XL-388 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 21 mg/mL (46.1 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.95 mL | 109.77 mL | 219.54 mL |
0.5 mM | 4.39 mL | 21.95 mL | 43.91 mL |
1 mM | 2.2 mL | 10.98 mL | 21.95 mL |
5 mM | 0.44 mL | 2.2 mL | 4.39 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2