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XL647 (Tesevatinib)

目录号: A11057
EGFR, HER2 and VEGFR 抑制剂
XL647 是一种口服生物利用度高的小分子 RTK 抑制剂,它能结合并抑制多种在肿瘤细胞增殖和肿瘤血管生成中起主要作用的酪氨酸受体激酶,包括 EGFRHER2ERBB2VEGFREphB4
Grouped product items
规格 价格 库存 数量
1mg
¥700.00
现货
2mg
¥1,050.00
现货
5mg
¥1,960.00
现货
10mg
¥3,500.00
现货
25mg
¥6,440.00
现货
50mg
¥10,500.00
现货
100mg
¥17,500.00
现货
10mM * 1mL in DMSO
¥1,820.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription XL647 is an orally bioavailable small-molecule RTK inhibitor that binds to and inhibits several tyrosine receptor kinases that play major roles in tumor cell proliferation and tumor vascularization, including EGFR, HER2, ERBB2, VEGFR and EphB4.
Targets
Target Value
产品信息
目录号 A11057
分子式 C24H27Cl2FN4O2
分子量 493.4
CAS号 781613-23-8
SMILES CN1CCCC(CCC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=CC(=C(C(=C4)Cl)Cl)F)OC
其他名称 XL 647, XL-647, EXEL-7647
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
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