Sara B Linker, .et al. , Curr Biol, 2022, Nov 21;32(22):4797-4807 PMID: 36228612
Renata Santos, .et al. , STAR Protoc, 2022, Mar 17;3(2):101261 PMID: 35313707
生物活性
Discription
Y-27632 is an ATP-competitive inhibitor of ROCK-I and ROCK-II, with Ki of 220 nM and 300 nM for ROCK-I and ROCK-II, respectively.
Targets
Target
Value
Cell Research
Cell Line
Type
Value
Description
References
产品信息
目录号
A21448
分子式
C14H21N3O
分子量
247.34
CAS号
146986-50-7
SMILES
O=C([C@@H]1CC[C@]([C@H](N)C)([H])CC1)NC2=CC=NC=C2
其他名称
Y27632, Y 27632
储存条件
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula: