YF-2

Name: YF-2
SKU: A21018

目录号: A21018

histone acetyltransferase activator

YF-2 Chemical Structure

CAS NO. 1311423-89-8

YF-2 is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC50s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease.

库存：现货

规格	价格	数量
5 mg	￥ 2,205.00
10 mg	￥ 3,801.00
50 mg	￥ 11,270.00
100 mg	￥ 22,540.00

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生物活性

溶解度 *

In vitro	DMSO	78 mg/mL (181.03 mM)
	Water	78 mg/mL (181.03 mM)
	Ethanol	78 mg/mL (181.03 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.21 mL	116.05 mL	232.1 mL
0.5 mM	4.64 mL	23.21 mL	46.42 mL
1 mM	2.32 mL	11.6 mL	23.21 mL
5 mM	0.46 mL	2.32 mL	4.64 mL

*The above data is based on the productmolecular weight 430.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A21018
作用机制	Activator (激活剂)
M. Wt	430.85
Formula	C20H22ClF3N2O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1311423-89-8
Synonyms	YF2, YF 2
SMILES	O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=C(OCC)C=CC=C2OCCN(C)C