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YKL-05-099

目录号: A20553
SIK 抑制剂
YKL-05-099 是一种盐诱导激酶(SIK)抑制剂。YKL-05-099 与 SIK1 和 SIK3 结合,其 IC50 分别约为 10 nM30 nM。YKL-05-099 对 SIK2 的抑制作用略弱(IC50=40 nM)。
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规格 价格 库存 数量
1mg
¥420.00
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5mg
¥805.00
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10mg
¥1,260.00
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25mg
¥2,240.00
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50mg
¥3,360.00
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100mg
¥4,760.00
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10mM * 1mL in DMSO
¥1,085.00
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生物活性
Discription YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. YKL-05-099 binds to SIK1 and SIK3 with IC50s of ~10 and ~30 nM, respectively. YKL-05-099 has slightly less potent SIK2-inhibitory (IC50=40 nM).
产品信息
目录号 A20553
分子式 C32H34ClN7O3
分子量 600.11
CAS号 1936529-65-5
SMILES O=C1N(C2=NC=C(OC)C=C2)C3=NC(NC4=CC=C(C5CCN(C)CC5)C=C4OC)=NC=C3CN1C6=C(C)C=CC=C6Cl
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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